Study of antioxidant activity of plant metabolites and composites based on them

Abstract

One of the urgent problems in the development of modern pharmaceuticals is the preparation of water-soluble forms of substance developed on the basis of plant raw materials. In this work the in vitro antioxidant activity of plant terpenoids, flavonoids and corresponding composites based on them was studied. As a result of our studies, we have found that the Pb/SE composite containing the flavonoid pinostrobin, as well as the sum of licorice extractives naked, showed relatively high antioxidant activity in vitro. This result may be due to the antioxidant effect of flavonoid pinostrobin, which is contained in the studied composite. The mechanism may lie in the process of free radical binding and chelation of metals of variable valence, which contributes to the inhibition of peroxide processes. It should also be noted the Leu/PVP composite (leucomisin / polyvinylpyrrolidone), which showed an antioxidant effect that is less pronounced compared to the antioxidant property of the Pb/SE composite.