The histochemical characteristic of pancreatic B-cells

Abstract

It is known that zinc possesses important role in processes of synthesis and formation of the deposited form of in pancreatic B-cells. Pancreas of many animals as of human contains a large amount of zinc. It is known also that some of chemicals and drugs capable to interact with zinc in B-cells that result destruction and death of cells. Authors have investigated the content of zinc inpancreatic islets of rabbit and features of localization in B-cells. It is established that the main amount of zinc concentrates in B-cells adjoining walls of blood capillaries through which there is hormone exit in blood. Authors suppose that destruction of pancreatic islets past intravenous injection of diabetogenic chemicals result for the first of all — destruction of B-cells adjoining to blood capillaries in islets.